Home > Meetings
|Thursday, April 28||
Chemistry Highlights at Northern Kentucky University
|Wednesday, April 20||
Analytical Discussion Group via Zoom
|Thursday, March 31||
Chemist and Technologist of the Year Awards at Miami University
|Tuesday, March 15||
Oesper Collection Becomes National Historic Chemical Landmark at University of Cincinnati
|Thursday, February 24||
"Dissolution Recycling of Polyolefins Using Alkane Solvents" at Mount St Joseph University
|Rescheduled Date TBD||
"A Tale of Two Entities: From Academia to Industry"
Analytical Discussion Group
Wednesday, April 20, 2022
12-1PM via Zoom
Click for REMOTE registration via Zoom
Join us for a Discussion Group in Analytical Chemistry focusing on “Advances in Real-time Molecular Monitoring". The ability to continuously monitor the concentration of specific molecules in the body is a long-sought goal of biomedical research. For this purpose, interstitial fluid (ISF) was proposed as the ideal target biofluid because its composition can rapidly equilibrate with that of systemic blood, allowing the assessment of molecular concentrations that reflect full-body physiology. In the past, continuous monitoring in ISF was enabled by microneedle sensor arrays. Yet, benchmark microneedle sensors can only detect molecules that undergo redox reactions, which limits the ability to sense metabolites, biomarkers, and therapeutics that are not redox active.
Our speaker, Dr. Yao Wu will present recent research efforts towards the first use of microneedle-supported electrochemical, aptamer-based (E-AB) sensors. Dr. Wu joined Dr. Netz Arroyo’s group as a postdoctoral fellow in the Department of Pharmacology and Molecular Sciences at Johns Hopkins University School of Medicine, where she has been working on the development of DNA-based electrochemical sensors to monitoring wound healing and chemotherapeutic-driven tumor shrinkage, as well as microneedle aptamer-based sensors for continuous, real-time molecular monitoring.